Scientist
CAMRIS

Gaithersburg, Maryland

This job has expired.


Overview

We are seeking a Scientist to support the National Institutes of Health's National Institute of Allergy and Infectious Diseases (NIAID) in Gaithersburg, MD. Our NIAID professional, technical, and scientific support personnel are part of a team focused on positively impacting millions of lives around the world. Candidates will work at a diverse and vibrant NIAID worksite to directly support ongoing research activities as a contractor team member. Take the next big step in your career and apply below to help us make a difference.

CAMRIS International is a dynamic clinical research and international development firm that achieves innovative solutions to health and development challenges through high-quality, cost-effective programs and research management services. We combine our proven systems with today's most effective, evidence-based best practices. Our core practice areas include: clinical research; vaccine research, microbiology and infectious disease research, development and production; biodefense; global health security; and HIV/AIDS programs.

Our employees enjoy a diverse, collegial environment where individual contributions matter at all levels. At CAMRIS, you will notably improve the lives of people at home and abroad.

Responsibilities

  • Contribute to the generation of stable cell lines for vaccine and therapeutic protein candidates including monoclonal antibodies, recombinant proteins, and virus-like particles.
  • Independently execute each step of the cell line development process including plasmid production, transfection, single cell cloning, clone expansion in static culture plates and shake flasks, fed-batch analysis, and clone stability studies.
  • Use automated platforms for clone selection and screening.
  • Prepare plasmid DNA using standard molecular cloning techniques.
  • Participate in cell line development platform design, optimization, and cycle-time reduction studies including methods for clone selection, expansion, ranking, and characterization.
  • Perform small-scale process development studies using various culture vessels including tissue culture plates, shake flasks, and small-scale bioreactors.
  • Generate stable pools and perform transient protein production for supply of reagent-grade material.
  • Provide laboratory support for medium preparation and ordering of supplies.
  • Perform maintenance of cell counters and bioprocess analyzers, coordination of service visits, and regular ordering of consumables.
  • Train other laboratory personnel on use of equipment and corresponding processes.
  • Write and review technical reports documenting process development studies and stable cell line generation work.
  • Work with other team members to generate experimental plans for process development studies.
  • Write and review standard operating procedures for cell line development processes and instrumentation.
  • Maintain complete documentation records, including a detailed and up-to-date laboratory notebook, to support regulatory filings.
  • Regularly communicate progress to team lead and present work to cell line development team.


Qualifications

  • B.S. in Biological Sciences with a minimum of 5 years of relevant work experience or M.S. in Biological Sciences with independent research experience in an academic or industrial setting.
  • Hands-on experience with aseptic technique and mammalian cell culture along with supporting technologies for cell line engineering including cell counting, high-throughput transfection, single-cell cloning, and flow cytometry.
  • Experience in preparing technical reports, standard operating procedures, and data presentations.
  • Ability to work independently to execute defined experiments and troubleshoot issues as needed to meet project timelines.
  • Ability to effectively communicate plans, results, challenges, and ideas to other team members in oral and written forms.
  • Familiarity with computer software for word processing and data analysis.
  • Experience in monoclonal antibody and/or vaccine production.


CAMRIS International LLC offers competitive salaries and comprehensive benefits. Please submit your resume online at www.CAMRIS.com . CAMRIS is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran status, disability status, or any other characteristic protected by any applicable federal, state, or local law.

Some positions or sites may require that the incumbent be fully vaccinated against COVID-19. Proof of vaccination may be required.

Employment is contingent upon successful completion of a Public Trust-level background check, a requirement for this position under an active federal contract. The background check process may include, but is not limited to the following: (1) contacting your professional references; (2) verification of previous employment, education and credentials; (3) a criminal background check; (4) use/abuse of federally-controlled substances; and (5) a department of motor vehicle check. Candidates must be prepared to fully-complete any required background check questionnaire during initial onboarding.


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