Senior Manager,Clinical Supply Chain Sourcing & Vendor Relations Project Manager
Immunocore

About the CompanyImmunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry's most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.

Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.

We strive to create a diverse and inclusive workplace, while seeking talented individuals to work with us across the many functions that will allow us to deliver new medicines to transform the lives of patients. You will work with outstanding people who together pioneer the research, development and commercialization of bi-specific TCR therapies. We aim to create an environment where individual contributions and initiatives can be maximized, while fostering a culture of collaboration, based on respect and integrity. We want each individual employee to own their career, as part of high-performing teams, and in the context of on-the-job and formal continuous development and training, as well as constructive feedback. We always strive to identify ways to improve what we do and how we do it, by asking questions, voicing opinions, exploring various approaches and staying connected with healthcare professionals, patients, academia and other key partners. Key ResponsibilitiesThe Clinical Supply Chain Sourcing and Vendor Relations Project Manager role will establish strong relationships with external vendors to work collaboratively and lead teams of internal teams experts (e.g. clinical supply chain, clinical operation, regulatory and strategy, portfolio & project management colleagues) in developing strategies for sourcing services and goods (e.g. comparator and co-meds) for IMMUNOCORE clinical studies, in line with related regulatory requirements and internal quality processes. The Clinical Supply Chain Sourcing and Vendor Relations Project Manager role holder will also interact with key internal stakeholders, particularly procurement, legal and finance colleagues.
KEY RESPONSIBILITIES
• Leads the identification and selection of new service and procurement vendors in line with IMMUNOCORE supplier compliance processes
• Builds and manages relationships with vendors and acts as the point of contact
• Leads technical scope related negotiations in joint operation meetings with vendors in collaboration with clinical supply chain and project teams
• Represents Clinical Supply Chain at periodic business review meetings with suppliers
• Acts as first point of contact for the escalation of issues with suppliers and drives business improvement by collecting and providing feedback on supplier performance through implemented KPIs.
• Provides sourcing options and recommendations to the project teams
• Manages the comparator/ co-med portfolio assignments to suppliers
• Evaluates and improves sourcing strategies for comparator/ co-med supplies such as quantities, supplier used and order frequency, by leveraging demand forecasts, market intelligence, cost and availability
• May undertake contract negotiations with suppliers in conjunction with Procurement colleagues and representatives from Clinical Supply Chain
• Identifies continuous improvement opportunities and leads process improvement activities to deliver business processes and technical solutions that align with various stakeholders
• Collaborates with clinical supplies planners and external vendors on comparator/ co-med supply management activities, including ordering schedule and sourcing plan according to clinical study timelines.
• Creates sourcing strategies to avoid impact to study timelines, while ensuring supply chain integrity
• Promotes a cost conscious environment to enable effective cost management and decisions
• Identifies and communicates risks related to sourcing products which may impact study timelines and proactively mitigates threats to sourcing activities
• Responsible for maintaining operations under GMP, GDP and global trade compliance
• Manages product sourcing related shipping issues (includes raising QIs and CAPAs as necessary) in collaboration with suppliers
• Keeps abreast of new and developing capabilities and strategies of suppliers in order to take advantage of new opportunities and maximize value for IMMUNOCORE
• Authors and revises procedures (SOPs and Work Instructions)
• Supports the RFP/RFQ process and obtains and reviews quotes
• Consults with Regulatory and Quality regarding product sourcing strategy
Experience & knowledge
Essential

• Ability to mentor clinical supplies managers and planners in evaluating the risk/reward tradeoffs in the timing and cost of comparator purchases given the known business intelligence on product availability
• Solid experience working with external service and product suppliers and sourcing and managing comparators and combo-meds for clinical studies
• Possesses extensive knowledge of comparator sourcing strategies (e.g., central sourcing, site sourcing, Pharmacy cards, etc)
• Can work well with ambiguity, assess options quickly and efficiently implement the best option (e.g., wholesaler, supply agreement, collaboration agreement) in alignment with IMMUNOCORE's culture and agreed timelines
• Appropriate depth of technical knowledge for the service or goods being sourced to be able to fully understand any risks to delivery and make best use of the experts on the project teams to make effective decisions
• Mature knowledge of the FDA, cGMP, GCP standards and regulatory guidance documents.
• Ability to lead in an agile, fast-paced environment with flexibility, empowerment, integrity, and authenticity
• Project management and strong analytical and problem-solving skills
• Strong knowledge of supply chain considerations (sourcing, manufacturing, distribution, quality, regulatory, finance, clinical operations)
• General understanding of clinical trial design, drug technical development, demand forecasting, import/export, and supply planning techniques
• Excellent verbal and written skills and attention to detail
• Strong interpersonal communication skills with the ability to simplify complex topics into key messages for non-subject matter experts
• Excellent organizational and computer skills (Word, Excel, PowerPoint, Outlook)
• Experience working in a matrix environment, possessing collaboration, influencing and negotiation skills to work effectively with internal cross-functional groups and external suppliers to meet aggressive clinical study timelines and patient needs
• Experience working with managing and forecasting budgets
• Strong personally credibility when interacting with external organizations
Desirable
• Knowledge and experience in Oncology therapeutic discipline
• Track record of working successfully with others in fact moving logistically complex projects
• Experience of drug usage forecasting/ supply and demand
• Experience of cold chain supply management and biopharmaceuticals
• Worked in all phases of clinical trials
Education & qualifications
• BSc degree in a relevant scientific subject or business management, or equivalent relevant and appropriate industry experience
• Desirable: Masters or PhD degree in a relevant subject
• Demonstrated computer skills; proven functional knowledge of Microsoft packages (MS Word, Excel, Power Point, Outlook, MS Project, SharePoint)