Sr Software Engineer I, Quantitative Biology, Moderna Genomics
ModernaTX, Inc.

The Role:

As part of our vision, Moderna is committed to invest in R&D to further expand our impact on patients. We are building an independent research and business unit for genomic medicines, called Moderna Genomics (mGx) based in Technology Square, Cambridge, MA. mGx will be an innovation engine for the company focused on discovering and delivering the next generation of in vivo gene editing and non-viral gene therapies. It is our intention to be an industry leader in genomic medicines.

Reporting to the Executive Director of Gene Editing Translational Bio, the Sr Software Engineer I, Quantitative Biology, Moderna Genomics will be a key member of a high performing team developing next generation gene editing technology within Moderna Genomics. You will be an innovative and collaborative computational biologist with expertise in gene editing analytics, broad skills in the area of mining genomics and high learning agility. In collaboration with experimental scientists, you will develop and apply computational methods to analyze large-scale custom datasets generated by the team to discover transformative gene editing technologies. The candidate must thrive in a fast pace environment with high expectations. Integrity, ability to share experimental issues and troubleshoot, curiosity, collaborative spirit, respect for people, exemplary work ethic and setting the bar high are key values to thrive in our Team.

Here's What You Will Do:

• Collaborate with our Gene Editing Platform team to develop and execute new NGS-based assays and screening methods
  
• Discover and characterize off-target editing through in silico prediction and analysis of data from standard and experimental off target assays
  
• Lead the design and creation of bioinformatics data pipelines to analyze results from routine and/or frequent assays
  
• Collaborate closely with stakeholders to ensure that project data are effectively utilized for high level impact
  
• Contribute to the maintenance of existing bioinformatic pipelines
  
• Interface and collaborate with broader computational science and bioinformatic teams in the ecosystem
  

Here's What You'll Bring to the Table:

• Ph.D. (or MS with comparable experience) in Computational Biology, Bioinformatics, or related quantitative discipline
  
• Strong scientific background, including an understanding of molecular biology and NGS techniques
  
• Strong coding skills using Python, R, git, Jupyter and familiarity with common bioinformatics tools
  
• Experience working with large datasets.
  
• Proficient with high performance computing, preferably on the cloud (i.e. AWS, GCP, Azure)
  
• Experience with statistical and machine learning methods a plus
  
• Experience with gene editing technologies and platforms as therapeutics
  
• Familiarity with long read next-generation sequencing platforms a plus
  
• Ability to work both independently and collaboratively
  
• Track record of success working in a fast-paced, cross-functional, and rapidly growing organization.
  
• Outstanding written and verbal communication skills
  

Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:

• Highly competitive and inclusive medical, dental and vision coverage options
• Flexible Spending Accounts for medical expenses and dependent care expenses
• Lifestyle Spending Account funds to help you engage in personal enrichment and self-care activities
• Family care benefits, including subsidized back-up care options and on-demand tutoring
• Free premium access to fitness, nutrition, and mindfulness classes
• Exclusive preferred pricing on Peloton fitness equipment
• Adoption and family-planning benefits
• Dedicated care coordination support for our LGBTQ+ community
• Generous paid time off, including:
  • Vacation, sick time and holidays
  • Volunteer time to participate within your community
  • Discretionary year-end shutdown
  • Paid sabbatical after 5 years; every 3 years thereafter
• Generous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents
• 401k match and Financial Planning tools
• Moderna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit options
• Complimentary concierge service including home services research, travel booking, and entertainment requests
• Free parking or subsidized commuter passes
• Location-specific perks and extras!

Candidates should be aware that Moderna currently maintains a policy requiring all US-based employees to be fully vaccinated against COVID-19 and receive a booster shot once eligible. Newly hired employees must be vaccinated and boosted prior to their employment start date. Moderna is an equal opportunity employer and will provide a reasonable accommodation to those unable to be vaccinated or receive a booster where it is not an undue hardship to the company to do so as provided under federal, state, and local law.

About Moderna

In over 10 years since its inception, Moderna has transformed from a research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across seven modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for rapid clinical and commercial production at scale. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna's capabilities have come together to allow the authorized use and approval of one of the earliest and most effective vaccines against the COVID-19 pandemic.

Moderna's mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and autoimmune diseases. Moderna has been named a top biopharmaceutical employer by Science for the past seven years. To learn more, visit www.modernatx.com.

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
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